Can I design a carrier board without EFM8SB10F8G and run the same OS flashed in developer kit correctly?

Hi, I’m designing a carrier board for the XAVIER, and I noticed that EFM8SB10F8G connected to CYPD4226 by I2C bus (I2C_CCG4_SCL & I2C_CCG4_SDA) in Developer Kit Carrier Board. If I remove EFM8SB10F8G and follow the solution of the Power-On (No MCU), Can XAVIER module run the same system flashed in developer kit correctly? Are there any modifications (such as device tree, driver) should be done?

Sure, it is OK to follow ‘No MCU’ solution, no other change needed.