The default method for delivering Chrome as a published application via XenApp requires the application to be run with no GPU acceleration. Any customer delivering Chrome as a published application will have used the switches as below:
"C:\Program Files (x86)\Google\Chrome\Application\chrome.exe" --allow-no-sandbox-job --disable-gpu
For a user to get a GPU accelerated experience in Chrome it should be published with with these switches:
"C:\Program Files (x86)\Google\Chrome\Application\chrome.exe" --allow-no-sandbox-job --disable-gpu-sandbox
Small changes, but enough to switch from no GPU to a fully accelerated application.