Dual 4500 ada with Mosaic display issue

Hi everyone,

I am using Dual 4500 ada and Mosaic to set up 8 2k displays into a 7680x2160.

While running some Unity applications, the display will have some lines and noises randomly appearing. I have checked all the cables and switch monitors to ensure they work fine. but the noises still exist. I have 2 of these set up and both machines are having the same noise issue,

Does anyone have any ideas? Thank you.