Graphics Card Performance and Complexity

How complex of a project can we do if we are running an Intel i9-9900k processor with 128GB of RAM, if we ran our same setup with an 11GB 2080Ti graphics card? A 24GB Quadro RTX6000? or a 48GB RTX 8000? We plan on running 4K and 8K video and we want to do special Efx like Houdini, and will also be running DaVinci Resolve and adding Stop-Motion animation.