How to best configure Windows drivers for multiple applications rendering at the same time?

The hardware is a mix of A10s and 3090s on AMD, on Windows 11 and Windows Server 2022.

For example, should hardware GPU scheduling be enabled or disabled? The machines seem really unstable with hardware GPU scheduling enabled.

I understand I could try all the settings everywhere and benchmark everything. I am hoping for some guidance as to what should or shouldn’t be configured.

What about inside Unity and Unreal itself? These are both using DX12 with NVIDIA Reflex plugins.