Good question but I guess the wrong place to ask for it. Doing a quick search over at the cuda performance forum yields:
https://forums.developer.nvidia.com/t/pascal-pny-p5000-enabling-ecc-slows-down-memory-accesses-20/72969
and old
https://forums.developer.nvidia.com/t/ecc-on-vs-ecc-off/20315
So seems it has quite an impact on memory bandwidth. Impact on a specific application depends how memory-bound it is.
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