Just upgraded to 4.5 on my xavier. The mouse motion is jerky. If you go from side to side with the pointer you see several distinct glitches in the motion. Nothing different in the hardware the 4.5 upgrade is the only difference. Very annoying. Tried another mouse with the same results.
Tried to reproduce your issue on JP-4.5, but I don’t see the mouse not smooth issue.
Are you using sdkmanager to upgrade your Xavier?
Yea I reflashed it and now its working fine. Have no idea what caused it.