Nvidia external chassis compatibility

[Apologies if this is not the appropriate forum]

I’m trying to find out if the S1070 and S870 Nvidia external chassis are compatible with the M2050 and other M-series GPUs. There is no information on this in the knowledge base and the datasheets only mention compatibility with the original cards that come with the chassis.

Does the S1070 and S870 require firmware or are they just a ‘dumb’ PCIe external bus?

It would be very interesting to upgrade the original cards with something more powerful.