Possible to use non-storage M.2 devices on Xavier?

I’d like to pair the Xavier with an Epiq Sidekiq M.2 board for software defined radio applications and was wondering if the interface on Xavier would work?

I see that Sidekiq has their M.2 card coming in Key-B and Key-M formfactor and Jetson-Xavier does have an M.2 Key-M slot. So, yes, you can use it.
Although as WayneWWW suggested, you may have to check with Sidekiq for the driver support for the Linux kernel version that runs on Jetson-Xavier.