The SGLang reviewer reported that there is no optimized kernel yet for FP4/sm121a (GB10), but they will support it as soon as it becomes available.
I think just like the other Blackwell GPUs it will take some time to get the necessary optimizations for the full potential of the GB10.
As for the use cases for the box the review of Level1Techs is worth watching. As they don’t stick to inference only.