Will someone describe a functional CentOS rig?

I want to work with OpenCL in Linux, specifically Cuda in CentOS 6.5 x86_64

At present I am unable to get any cuda-enabled driver to work, and it may be a system compatibility issue. I would like to learn about any configuration that can do Cuda/Centos.

It’s possible that it’s an AMD-CPU issue - what CPU are people using?

TIA