page-locked just means that the memory pages are locked and will not go and change physical addresses or be swapped out to disk by the OS. You can still write to them just like any other pointer.
It can be a factor of two or more depending on your motherboard. You can test with the bandwidthTest program included in the SDK. Without any options, it uses regular malloc’d memory. With the “–memory=pinned” it runs with page-locked memory.