Hi therealmatiss,
Are you using the devkit or custom board for Orin Nano?
What’s the Jetpack version in use?
If you want to run UART in DMA mode, please refer to the following thread for the fix.
Solved: UART/Serial Port not working after upgradint to Jetpack 6.2.2 (Orin Nano/NX) - #7 by KevinFFF