compiler options

Is there a way to improve the execution time performance by tweaking compiler flags?
I’m using the following options:

set COMPILER=nvcc
set COMPFLAGS= -c -arch=compute_20 -code=sm_20 -Xcompiler “/c /Zp8 /GR /W3 /EHs /D_CRT_SECURE_NO_DEPRECATE /D_SCL_SECURE_NO_DEPRECATE /D_SECURE_SCL=0 /DMATLAB_MEX_FILE /nologo /MD”
set OPTIMFLAGS=-Xcompiler “/O2 /Oy- /DNDEBUG”
set DEBUGFLAGS=-Xcompiler “/Zi /Fd”%OUTDIR%%MEX_NAME%%MEX_EXT%.pdb""

Thank you