Parabricks

Topic	Replies	Views	Activity
Welcome to the NVIDIA Parabricks Developer Forum Welcome to our Developer Forum! This Developer Forum is open to the entire Parabricks community and is a great place to ask questions, exchange knowledge, and connect with fellow Parabricks users. If you have purchased…	1	2188	May 25, 2024
Latest Parabricks Releases New features, performance improvements and bug fixes by release.	4	524	October 21, 2025
Pbrun haplotypecaller running error	6	148	September 4, 2026
Deepvariant error: deep_common2/vcf.cpp:1801] Allele ->A,A not found in probability dictionary ai , deepvariant	3	71	August 21, 2026
Pbrun genotypegvcf 4.7.1-1 stalls in PBBgzfFile.cpp when reading a 1326-sample GATK CombineGVCFs file with records larger than 64 KiB ai	1	33	August 14, 2026
Student Request for Brev.dev Credits - Regis University (PCOS Detection Project)	1	79	July 13, 2026
Kmer size control in haplotypecaller cuda	1	62	July 2, 2026
Fq2bam postsort/BQSR hangs and crashes on large WGS tumor samples — reproducible across Parabricks 4.6 and 4.7, two different GPU setups fq2bam	3	111	July 1, 2026
Rna_fq2bam GPU-STAR: illegal memory access at ~1,000,000 collapsed junctions, independent of --max-collapsed-junctions ai , bug	0	63	July 1, 2026
Ready2Run Parabricks DeepVariant on HealthOmics: silent 0-byte VCF from TensorRT engine version mismatch ai , fq2bam , deepvariant	0	57	June 20, 2026
Parabricks fq2bam CRAM output fails samtools index with CRAM slice offset does not match landmark ai , fq2bam	2	75	June 3, 2026
Why Does NVIDIA Parabricks Become Slower as More Samples Are Processed?	3	119	May 14, 2026
Bcftoolsmpileup and bcftoolscall remove in Parabricks 4.x?	1	53	May 13, 2026
[Help] Parabricks genotypegvcf for Multi-sample Joint Genotyping — Do I need to pre-merge GVCFs?	1	101	May 13, 2026
Standalone BQSR crashing but full FQ2BAM succeeding fq2bam	1	68	May 1, 2026
Memory leak crashing run at MarkDuplicates/BQSR stage in Fq2Bam ai , fq2bam	17	329	April 26, 2026
Why pbrun genotypegvcf only recognizes the last input file when processing multiple GVCFs on a large genome？	0	83	April 25, 2026
Can Parabricks generate CSI index when running fq2bam? fq2bam	2	87	April 22, 2026
Deepvariant_germline --keep-duplicates fq2bam	2	89	April 13, 2026
CRAM 3.1 Support deepvariant	1	77	March 31, 2026
Question about CPU thread scaling and control in Parabricks	2	89	March 31, 2026
Outputting both VCF and gVCF deepvariant	4	129	March 31, 2026
How to run STAR-WASP mode in pbrun rna_fq2bam?	2	84	March 25, 2026
Sorting clarification for markdup	5	214	March 18, 2026
GenotypeGVCF in Parabricks 4.3.2 not using GPUs and ending with error	4	97	March 17, 2026
Fq2bam stalls in single-end recovery mode fq2bam	3	140	March 9, 2026
Why was it that I was able to successfully run fq2bam but it didn't work properly? fq2bam	0	42	March 9, 2026
Options for fq2bam/markdup to only handle optical duplicates and support multi-lane samples fq2bam	1	69	February 20, 2026
Deepsomatic Invalid tumor sample name input cuda , gpu	1	80	February 17, 2026
Minimap signal error ai	0	57	February 13, 2026

Welcome to the NVIDIA Parabricks Developer Forum

Welcome to our Developer Forum! This Developer Forum is open to the entire Parabricks community and is a great place to ask questions, exchange knowledge, and connect with fellow Parabricks users. If you have purchased…

1

2188

May 25, 2024

Latest Parabricks Releases

New features, performance improvements and bug fixes by release.

4

524

October 21, 2025

Pbrun haplotypecaller running error

6

148

September 4, 2026

Deepvariant error: deep_common2/vcf.cpp:1801] Allele ->A,A not found in probability dictionary

ai , deepvariant

3

71

August 21, 2026

Pbrun genotypegvcf 4.7.1-1 stalls in PBBgzfFile.cpp when reading a 1326-sample GATK CombineGVCFs file with records larger than 64 KiB

ai

1

33

August 14, 2026

Student Request for Brev.dev Credits - Regis University (PCOS Detection Project)

1

79

July 13, 2026

Kmer size control in haplotypecaller

cuda

1

62

July 2, 2026

Fq2bam postsort/BQSR hangs and crashes on large WGS tumor samples — reproducible across Parabricks 4.6 and 4.7, two different GPU setups

fq2bam

3

111

July 1, 2026

Rna_fq2bam GPU-STAR: illegal memory access at ~1,000,000 collapsed junctions, independent of --max-collapsed-junctions

ai , bug

0

63

July 1, 2026

Ready2Run Parabricks DeepVariant on HealthOmics: silent 0-byte VCF from TensorRT engine version mismatch

ai , fq2bam , deepvariant

0

57

June 20, 2026

Parabricks fq2bam CRAM output fails samtools index with CRAM slice offset does not match landmark

ai , fq2bam

2

75

June 3, 2026

Why Does NVIDIA Parabricks Become Slower as More Samples Are Processed?

3

119

May 14, 2026

Bcftoolsmpileup and bcftoolscall remove in Parabricks 4.x?

1

53

May 13, 2026

[Help] Parabricks genotypegvcf for Multi-sample Joint Genotyping — Do I need to pre-merge GVCFs?

1

101

May 13, 2026

Standalone BQSR crashing but full FQ2BAM succeeding

fq2bam

1

68

May 1, 2026

Memory leak crashing run at MarkDuplicates/BQSR stage in Fq2Bam

ai , fq2bam

17

329

April 26, 2026

Why pbrun genotypegvcf only recognizes the last input file when processing multiple GVCFs on a large genome？

0

83

April 25, 2026

Can Parabricks generate CSI index when running fq2bam?

fq2bam

2

87

April 22, 2026

Deepvariant_germline --keep-duplicates

fq2bam

2

89

April 13, 2026

CRAM 3.1 Support

deepvariant

1

77

March 31, 2026

Question about CPU thread scaling and control in Parabricks

2

89

March 31, 2026

Outputting both VCF and gVCF

deepvariant

4

129

March 31, 2026

How to run STAR-WASP mode in pbrun rna_fq2bam?

2

84

March 25, 2026

Sorting clarification for markdup

5

214

March 18, 2026

GenotypeGVCF in Parabricks 4.3.2 not using GPUs and ending with error

4

97

March 17, 2026

Fq2bam stalls in single-end recovery mode

fq2bam

3

140

March 9, 2026

Why was it that I was able to successfully run fq2bam but it didn't work properly?

fq2bam

0

42

March 9, 2026

Options for fq2bam/markdup to only handle optical duplicates and support multi-lane samples

fq2bam

1

69

February 20, 2026

Deepsomatic Invalid tumor sample name input

cuda , gpu

1

80

February 17, 2026

Minimap signal error

ai

0

57

February 13, 2026

Healthcare & Life Sciences Parabricks