185.18.10 CUDA does not work, 180.X sires sorta works....

I presume you are basing this “it doesn’t work” purely on the fact that gpugrid doesn’t complete tasks. You mentioned you have installed the CUDA 2.2 toolkit. If you install the 2.2 SDK you should be able to build the examples therein and see if they pass or not. That will provide independent confirmation of whether the CUDA driver is working properly or not.