BWA version 0.7.15 in parabrick

Healthcare & Life Sciences Parabricks
1

Hi, I am using parabrick pipeline for analysing whole genome data. However, I noticed that the bwa version used in the pipeline is old (0.7.15) as 0.7.17 is available since 2017. Is there any specific reason for using 0.7.15 and not 0.7.17. Will it impact downstream analysis (variant calling etc)?

2

Hey @a.farswan,

BWA generates the same exact BAM file for all versions starting with 0.7.15 so there should be no effect on your downstream analysis.

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3

version 0.7.15 misses the option -5SP important to map HiC data. Any plan to update do 0.7.18?