Jetson Nano
189PIN: I2C1_SCL ( +3.3V, On Module 2.2K pull-up )
191pin: I2C1_SDA ( +3.3V, On Module 2.2K pull-up )
“Is there any issue if I connect a 47K resistor as a pull-up on an open-drain output?”
R = 1 / ( (1/2.2K) + (1/4.7K) ) = 2.1K ohm
Refer to I2C bus specifications for pull up value recommendations and calculations. 47K pull up will be too weak and depends on your I2C bus trace lengths and loading/bus capacitance amongst other factors.
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