Matlab for TX1?

Is it possible to use Matlab and simulink with the aarch64 architecture?

My understanding is currently native Matlab binaries are not provided for interactively running Matlab sessions on ARM, but I do believe something from MathWorks is in the works to support the platform. This is referring to running Matlab environment from the Jetson.

If you are referring to synthesis using ARM Coder or Simulink Coder, you may want to refer to this page and may find it helpful to contact MathWorks support for further information regarding their product and ARM support. Jetson TX1 uses ARM Cortex-A57, which is not explicitly called out on their page above but may be intended.