Falke, It’s unclear if this is a CUDA or OpenGL issue. Can you provide more detail regarding your application, what version of Nsight you are using, and how you are using Nsight.
So, I use Nsight VS Edition 2.2 with just an option from Nsight tools list “Start CUDA Debugging”.
Regarding my application: in general it’s kind of image processing, where a 2D float texture is used to store the information. OpenGl is used only for output of the final picture. Therefore I don’t think that problem is there - result is shown in debug mode the same way.