nVidia Quadroplex 2200 S4 VmWare esxi passthrough

Iam running a Dell R710 testlab, and can get esxi to passthrough the nVidia Quadroplex 2200 S4
The GPU is detected by esxi, and i can check it in the passthrough list, but still after rebooting the esxi host the passthrouh is not activated.

What can I do?

That technology is not on the VMware HCL, so it’s not going ot be supported.

Is there an other hypervisor that will support passthrough for this nvidia device or is the only option to run the OS directly on the iron.

… for the nvidia device to work

Not likely to be supported in any given its age.