Jetson Nano PiOLED, fan, KB mouse failure

hello spyder19,

please refer to this topic for the port connections, Serial port 1 data loss occasionally - #5 by yzh03

you’re using Windows Operation System, right?
in my experience, Serial Port Utility just works with Windows7 and Windows10.

please also have a try by stopping and disabling the nvgetty service.
execute below commands on Nano to starts a console on ttyTHS1.
$ systemctl stop nvgetty
$ systemctl disable nvgetty