when Nsight 5.3 is installed it seems to mess around with the working directory of my solutions. I have some custom dlls in my working directory. Whenever I debug my application with Nsight installed those dlls cannot be found anymore. This happens with both, the nsight graphics debugger and the local windows debugger (which should have nothing to do with nsight, right?). I checked all the projects properties twice and recompiled everything completely. As soon as I uninstall Nsight it works again.
Edit: It seems like Nsight ignores the working directory completely (also outside visual studio when running the app from a shortcut with a custom working dir). A workaround is to set the VS output directory to the same value as the working directory. Would be nice if that can be fixed.